Evaluation of clinical and laboratory variables associated with anemia in pediatric patients on hemodialysis

Autor: Jonathan S. de Freitas, Paulo Sucasas Costa, Luciane Rezende Costa, Alessandra V. Naghettini
Jazyk: portugalština
Rok vydání: 2015
Předmět:
Zdroj: Jornal de Pediatria (Versão em Português), Vol 91, Iss 1, Pp 87-92 (2015)
Druh dokumentu: article
ISSN: 2255-5536
DOI: 10.1016/j.jpedp.2014.05.009
Popis: Objective: To identify the occurrence of anemia in pediatric patients on hemodialysis and the association between hemoglobin levels and anemia in CKD‐related variables. Methods: This was a retrospective study. Patients aged up to 18 years with chronic kidney disease undergoing hemodialysis at this service between January of 2009 and December of 2010 were selected. Clinical and laboratory data were obtained from medical records. Statistical analysis was performed with chi‐squared test, Student's t‐test and general estimating equations (GEE) using SPSS 20.0, assuming a significance level of 5%. Results: A total of 357 medical records depicting the monthly evolution of 29 patients were analyzed. The most common etiology for chronic kidney disease was malformations of the genitourinary tract (28%). Hemoglobin showed a mean (standard deviation) value of 9.20 (1.8) g/dL, with the occurrence of anemia in 65.3% of cases. Anemia was associated with hospitalization; antibiotic use; transfusion; use of intravenous iron hydroxide; low values of creatinine, hematocrit, and albumin; and high values of ferritin, aluminum, and equilibrated Kt/V (p
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