Clinical characterization of patients with primary aldosteronism plus subclinical Cushing’s syndrome

Autor:	Shigemitsu Yasuda, Yusuke Hikima, Yusuke Kabeya, Shinichiro Iida, Yoichi Oikawa, Masashi Isshiki, Ikuo Inoue, Akira Shimada, Mitsuhiko Noda
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Primary aldosteronism Subclinical Cushing’s syndrome Adrenal tumor Maximum tumor diameter Diabetes mellitus Serum potassium Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-9 (2020)
Druh dokumentu:	article
ISSN:	1472-6823
DOI:	10.1186/s12902-020-0490-0
Popis:	Abstract Background Primary aldosteronism (PA) plus subclinical Cushing’s syndrome (SCS), PASCS, has occasionally been reported. We aimed to clinically characterize patients with PASCS who are poorly profiled. Methods A population-based, retrospective, single-center, observational study was conducted in 71 patients (age, 58.2 ± 11.2 years; 24 males and 47 females) who developed PA (n = 45), SCS (n = 12), or PASCS (n = 14). The main outcome measures were the proportion of patients with diabetes mellitus (DM), serum potassium concentration, and maximum tumor diameter (MTD) on the computed tomography (CT) scans. Results The proportion of DM patients was significantly greater in the PASCS group than in the PA group (50.0% vs. 13.9%, p
Databáze:	Directory of Open Access Journals
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