Abundant lipid and protein components of drusen.

Autor: Lan Wang, Mark E Clark, David K Crossman, Kyoko Kojima, Jeffrey D Messinger, James A Mobley, Christine A Curcio
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: PLoS ONE, Vol 5, Iss 4, p e10329 (2010)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0010329
Popis: Drusen are extracellular lesions characteristic of aging and age-related maculopathy, a major retinal disease of the elderly. We determined the relative proportions of lipids and proteins in drusen capped with retinal pigment epithelium (RPE) and in RPE isolated from non-macular regions of 36 human retinas with grossly normal maculas obtained
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