Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature

Autor: Takuro Noguchi, Toshirou Fukushima, Hiroaki Hara, Nodoka Sekiguchi, Takashi Kobayashi, Takesumi Ozawa, Daisuke Gomi, Tomonobu Koizumi
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-5 (2020)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/s13256-020-02420-x
Popis: Abstract Background Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma. Case presentation Here, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma. Imaging studies revealed a 26 cm tumor in his right scrotum and lung metastases at presentation. He underwent radical orchiectomy followed by systemic chemotherapies. Pathological findings of the resected primary tumor confirmed a dedifferentiated liposarcoma. He then started chemotherapy treatment with gemcitabine plus docetaxel. His disease status was stable for 1 year. Eribulin was used for second-line chemotherapy. He had a relapse at 5 months after eliburin and died at 22 months after diagnosis. Conclusion Early diagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma. However, a giant paratesticular liposarcoma could cause metastases, and systemic chemotherapy may be helpful for prolonging survival in patients with metastatic paratesticular liposarcoma.
Databáze: Directory of Open Access Journals
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