Differential diagnosis of benign and malignant patchy ground-glass opacity by thin-section computed tomography

Autor: Zhang-rui Liang, Min Ye, Fa-jin Lv, Bin-jie Fu, Rui-yu Lin, Wang-jia Li, Zhi-gang Chu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 1471-2407
DOI: 10.1186/s12885-022-10338-4
Popis: Abstract Background Previous studies confirmed that ground-glass nodules (GGNs) with certain CT manifestations had a higher probability of malignancy. However, differentiating patchy ground-glass opacities (GGOs) and GGNs has not been discussed solely. This study aimed to investigate the differences between the CT features of benign and malignant patchy GGOs to improve the differential diagnosis. Methods From January 2016 to September 2021, 226 patients with 247 patchy GGOs (103 benign and 144 malignant) confirmed by postoperative pathological examination or follow-up were retrospectively enrolled. Their clinical and CT data were reviewed, and their CT features were compared. A binary logistic regression analysis was performed to reveal the predictors of malignancy. Results Compared to patients with benign patchy GGOs, malignant cases were older (P
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