| Autor: |
Radha Dhingra, Fan He, Erika F.H. Saunders, Daniel A. Waschbusch, Edward O. Bixler, Jody L. Greaney, Alison R. Swigart, Laila Al-Shaar, Vernon M. Chinchilli, Jeff D. Yanosky, Duanping Liao |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Psychiatry Research Communications, Vol 3, Iss 3, Pp 100139- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2772-5987 |
| DOI: |
10.1016/j.psycom.2023.100139 |
| Popis: |
Background: We examined the relationship between baseline cardiovascular (CV) disease/risk factors and longitudinally-collected scores on the patient health questionnaire (PHQ-9) depression scale using an outpatient sample of individuals with mental illness (PCARES Registry, 2015–2020). Methods: Individuals with ≥2 repeated PHQ-9 assessments over one-year from the baseline PHQ-9 measurement (N = 2110) were included for trajectory modeling, with five depression symptom severity trajectory groups determined a priori (lowest, lower, middle, higher, and highest). Proportional odds models provided the association between baseline CV disease/risk factors and the odds of belonging to the more severe depression symptom trajectory group. In a sub-sample (baseline PHQ-9 score ≥10), linear-mixed effects models provided the association between baseline CV disease/risk factors and longitudinal PHQ-9 scores (N = 1118). Results: 2110 individuals included 65% females, 87% non-Hispanic white, 50% in lower and middle severity groups, with mean ± SD age: 43.0 ± 16.8 years and PHQ-9 score: 10.8 ± 7.0. Adjusting for socio-demographics and BMI [OR (95% CI)]: individuals with baseline hypertension [1.4 (1.2–1.7)], diabetes [1.3 (1.0–1.6)], dyslipidemia [1.2 (1.0–1.4)], tobacco use [2.0 (1.6–2.6)], and higher number of CV disease/risk factors (P-trend |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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