HIV-HBV coinfection and liver fibrosis in long time monitored patients from the former Romanian pediatric HIV cohort – a small study single center experience
| Autor: | Giorgiana-Nicoleta Lungu, Florentina Dumitrescu, Anca Duduveche, Andreea Marcu, Lucian-Ion Giubelan |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Romanian Journal of Infectious Diseases, Vol 27, Iss 1, Pp 16-20 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1454-3389 2069-6051 |
| DOI: | 10.37897/RJID.2024.1.2 |
| Popis: | The aim of this study was to determine the degree of liver fibrosis with the help of a non-invasive method - transient elastography - in a long term monitored HIV-HBV coinfected group of patients (from the former Romanian pediatric cohort) and to assess the implication of various factors as potential risk factors for the development of liver fibrosis. We have reviewed a total of 636 patients (Px) that were in the evidence of the HIV Department of the “Victor Babes” Hospital of Infectious Diseases of Craiova, from which we randomly selected a group of 37 patients that are monthly attending the HIV department. Mean age of the patients was 34.03±2 years old and they were monitored for a long period of time, mean duration of monitorization was 26.11±4.31 years. Patients have been split into group A (13 Px) with various degrees of liver fibrosis and group B (24 Px) without liver fibrosis; the mean value of liver stiffness was higher in group A vs group B 11.27±5.72 vs.4.93±0.98 kPa, p |
| Databáze: | Directory of Open Access Journals |
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