Autor: |
Youcai Li, Yin Zhang, Zhihua Guo, Peng Hou, Jie Lv, Miao Ke, Shaoyu Liu, Siwen Li, Weiqiang Yin, Jianxing He, Xinlu Wang |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Cancer Imaging, Vol 24, Iss 1, Pp 1-15 (2024) |
Druh dokumentu: |
article |
ISSN: |
1470-7330 |
DOI: |
10.1186/s40644-024-00701-y |
Popis: |
Abstract Background This study investigates the value of fluorine 18 ([18F])-labeled fibroblast activation protein inhibitor (FAPI) for lymph node (LN) metastases in patients with stage I-IIIA non-small cell lung cancer (NSCLC). Methods From November 2021 to October 2022, 53 patients with stage I-IIIA NSCLC who underwent radical resection were prospectively included. [18F]-fluorodeoxyglucose (FDG) and [18F]FAPI examinations were performed within one week. LN staging was validated using surgical and pathological findings. [18F]FDG and [18F]FAPI uptake was compared using the Wilcoxon signed-ranks test. Furthermore, the diagnostic value of nodal groups was investigated. Results In 53 patients (median age, 64 years, range: 31–76 years), the specificity of [18F]FAPI for detecting LN metastasis was significantly higher than that of [18F]FDG (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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