Pre-diabetes and diabetic neuropathy are associated with low serum levels of interleukin-9

Autor: Noorulhuda F. Khalaf, Aaiad H. Al-rikabi, Isam N. Salman, Yahya D. Saihood, Shahad W. Nassurat, Ola H. Jasim, Ali H. Ad’hiah
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Beni-Suef University Journal of Basic and Applied Sciences, Vol 12, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 2314-8543
DOI: 10.1186/s43088-023-00412-6
Popis: Abstract Background Interleukin-9 (IL-9) is a cytokine that has recently been proposed to be associated with type 2 diabetes mellitus (T2DM) risk, but the role it plays in the development of pre-diabetes (PD) and diabetic neuropathy (DN) is unknown. Therefore, this study analyzed serum IL-9 levels in individuals with PD (n = 89), T2DM patients without DN (n = 66), T2DM patients with DN (n = 21), and non-diabetic controls (n = 84) using an ELISA kit. Results Serum IL-9 levels (median and interquartile range) were significantly lower in the PD (18.9 [12.6–22.1] pg/mL; probability [p]
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