Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

Autor:	Qingtian Guan, Talal S. Almutairi, Tahani Alhalouli, Arnab Pain, Faisal Alasmari
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Mycobacterium leprae metagenomics drug resistance imported infectious diseases tuberculosis and other mycobacteria rpoB Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 26, Iss 3, Pp 615-617 (2020)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2603.190661
Popis:	Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/9260028c45f847a3913f689f083067b8 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF