| Autor: |
Gabriella Kertész, Krisztián Kállay, Csaba Kassa, Marianna Zombori, Imre Bodó, Csongor Kiss, István Szegedi, Gergely Kriván |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Pathology and Oncology Research, Vol 28 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1532-2807 |
| DOI: |
10.3389/pore.2022.1610171 |
| Popis: |
The first-line treatment of severe aplastic anemia is allogeneic hematopoietic stem cell transplantation with a matched sibling donor. However, co-morbidities of the identical donor can make donation difficult. We present a transplantation where in parallel with the patient’s conditioning treatment, the preparation of the donor with severe hemophilia A required a special management with perioperative factor VIII substitution. Donation was successful without complications, and 18 months after transplantation, the patient and his donor are well without any long-term sequelae. To our knowledge, this is the first reported succesfull transplantation with hemophilic child serving as a bone marrow donor. The procedure did not mean a significant risk to donor health, so donors with hemophilia should not be excluded from donation. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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