Botulinum Neurotoxin Therapy in the Clinical Management of Laryngeal Dystonia

Autor: Winnie Yeung, Amanda L. Richards, Daniel Novakovic
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Toxins, Vol 14, Iss 12, p 844 (2022)
Druh dokumentu: article
ISSN: 14120844
2072-6651
DOI: 10.3390/toxins14120844
Popis: Laryngeal dystonia (LD), or spasmodic dysphonia (SD), is a chronic, task-specific, focal movement disorder affecting the larynx. It interferes primarily with the essential functions of phonation and speech. LD affects patients’ ability to communicate effectively and significantly diminishes their quality of life. Botulinum neurotoxin was first used as a therapeutic agent in the treatment of LD four decades ago and remains the standard of care for the treatment of LD. This article provides an overview of the clinical application of botulinum neurotoxin in the management of LD, focusing on the classification for this disorder, its pathophysiology, clinical assessment and diagnosis, the role of laryngeal electromyography and a summary of therapeutic injection techniques, including a comprehensive description of various procedural approaches, recommendations for injection sites and dosage considerations.
Databáze: Directory of Open Access Journals
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