Potassium Measures and Their Associations with Glucose and Diabetes Risk: The Multi-Ethnic Study of Atherosclerosis (MESA).

Autor: Ranee Chatterjee, Leila Zelnick, Kenneth J Mukamal, Jennifer A Nettleton, Bryan R Kestenbaum, David S Siscovick, Joachim H Ix, Russell Tracy, Andrew N Hoofnagle, Laura P Svetkey, David Edelman, Ian H de Boer
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: PLoS ONE, Vol 11, Iss 6, p e0157252 (2016)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0157252
Popis: Recent studies have found low-normal potassium (K) to be associated with increased diabetes risk. We sought to verify these associations in a multi-ethnic US cohort; and to determine if these associations extend to US Hispanics and Asian-Americans.We analyzed data from Multi-Ethnic Study of Atherosclerosis (MESA) participants who were free-of-diabetes at baseline. We examined cross-sectional associations between measures of K-serum, dietary, and urine-with fasting glucose and HOMA-IR. We examined longitudinal associations between K and diabetes risk over 8 years.In multivariable models, compared to those with higher serum K (≥4.5mmol/L), those with lower serum K (
Databáze: Directory of Open Access Journals