A Study on the Effects of Repetitive Transcranial Magnetic Stimulation on EEG Microstate in Patients With Parkinson’s Disease
| Autor: | Shuo Liu, Shuo Yang, Keke Feng, Chen Wang, Lei Wang |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 32, Pp 3369-3377 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1534-4320 1558-0210 |
| DOI: | 10.1109/TNSRE.2024.3418846 |
| Popis: | Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technology that can modulate cerebral cortical excitability. Electroencephalography (EEG) microstate analysis is an important tool for studying dynamic changes in brain functional activity. This study explores the pathophysiological changes in Parkinson’s disease (PD) patients by analyzing the EEG microstate of PD patients, and analyzes the impact of rTMS on the clinical symptoms of PD patients. In a trial, 25 patients with PD and 18 healthy subjects of the same age were included. The clinical scale (the third part of Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale (UPDRS-III) and Montreal Cognitive Assessment (MoCA)) scores of each patient were evaluated and the microstate characteristic parameters of all subjects were calculated. 10 Hz rTMS was used to stimulate the bilateral primary motor cortex (M1) of PD patients. After two weeks of treatment (10 times), the clinical scale score of each patient was re-evaluated and the microstate characteristic parameters were calculated. At the baseline, the occurrence, duration and coverage of microstate C in PD patients were significantly higher than those in healthy controls (P |
| Databáze: | Directory of Open Access Journals |
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