| Popis: |
In response to the shortcomings of magnesium oxychloride cement (MOC), which has excellent with outstanding mechanical properties and favorable bioactivity but poor water resistance, strontium hydrogen phosphate (SrHPO _4 ) was used as a water resistance modifier for MOC in the paper, and the effects of SrHPO _4 on the strength, water resistance, in vitro degradation and bioactivity of MOC were investigated; the results showed that SrHPO _4 could enhance the water resistance of MOC, in which the initial strength of MOC containing 4.0 wt% SrHPO _4 was 92.3 ± 2.5 MPa, and the strength was still 8.2 ± 0.9 MPa after 84 d of immersion in SBF solution; the degradation experiments of the samples in SBF solution showed that the degradation of SrHPO _4 -MOC was controlled, and the low alkaline environment created by the degradation promoted the deposition of hydroxyapatite on the cement surface, it indicated that SrHPO _4 -MOC material had good degradation properties and bioactivity; cell experiments showed that compared with MOC, SrHPO _4 -MOC was noncytotoxic and could promote cell proliferation, which was expected to be a new material for bone repair. |
