Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug

Autor: Samar M. Abouelatta, Ahmed A. Aboelwafa, Omaima N. El-Gazayerly
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Drug Delivery, Vol 25, Iss 1, Pp 1161-1174 (2018)
Druh dokumentu: article
ISSN: 1071-7544
1521-0464
10717544
DOI: 10.1080/10717544.2018.1474969
Popis: Gabapentin (GBP), an antiepileptic and anti-neuropathic agent, suffers from short half-life (5–7 h), has narrow absorption window, and is absorbed via carrier-mediated mechanism resulting in frequent dosing, poor compliance, and poor bioavailability (
Databáze: Directory of Open Access Journals
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