| Autor: |
Naledi Mannathoko, Mosepele Mosepele, Robert Gross, Rachel M. Smith, Kevin Alby, Laurel Glaser, Melissa Richard-Greenblatt, Rebekah Dumm, Aditya Sharma, Anne Jaskowiak-Barr, Leigh Cressman, Kgotlaetsile Sewawa, Laura Cowden, Emily Reesey, Dimpho Otukile, Giacomo M. Paganotti, Margaret Mokomane, Ebbing Lautenbach |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 122, Iss , Pp 313-320 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2022.06.004 |
| Popis: |
Objectives: Although extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) are a global challenge, data on these organisms in low- and middle-income countries are limited. In this study, we sought to characterize colonization data critical for greater antibiotic resistance surveillance efforts. Methods: This study was conducted in three hospitals and six clinics in Botswana. We conducted ongoing surveillance of adult patients in hospitals and clinics and adults and children in the community. All participants underwent rectal swab sampling to identify ESCrE and CRE. Results: Enrollment occurred from January 15, 2020, to September 4, 2020, but paused from April 2, 2020, to May 21, 2020, because of a countrywide COVID-19 lockdown. Of 5088 individuals approached, 2469 (49%) participated. ESCrE colonization prevalence was 30.7% overall (43% for hospital participants, 31% for clinic participants, 24% for adult community participants, and 26% for child community participants) (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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