Development and butyrylcholinesterase/monoamine oxidase inhibition potential of PVA-Moringa oleifera developed nanofibers

Autor: Nihal Abdalla Ibrahim, Saima Bibi, Abida Kalsoom Khan, Ghulam Murtaza
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Experimental Nanoscience, Vol 17, Iss 1, Pp 34-46 (2022)
Druh dokumentu: article
ISSN: 1745-8080
1745-8099
17458080
DOI: 10.1080/17458080.2021.2016712
Popis: The objective of the current research was to study the effects of polyvinyl alcohol (PVA) electrospun nanofibers loaded with different concentrations of leaf extract of Moringa oleifera (MO) on butyrylcholinesterase (BuChE), monoamine oxidase A (MAO A) and monoamine oxidase B (MAO B) enzymes. The MO-loaded PVA nanofibers were investigated for their inhibitory effect on BuChE and MAO A & B enzymes. The characterization of the fabricated nanofibers was performed by using SEM, FTIR and XRD. The results showed that increasing the concentration of MO, the enzyme inhibition capability of electrospun nanofibers was greatly (p
Databáze: Directory of Open Access Journals
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