3D Characterization of corneal deformation using ultrasound speckle tracking
| Autor: | Keyton Clayson, Elias Pavlatos, Yanhui Ma, Jun Liu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Innovative Optical Health Sciences, Vol 10, Iss 6, Pp 1742005-1-1742005-8 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1793-5458 1793-7205 17935458 47771488 |
| DOI: | 10.1142/S1793545817420056 |
| Popis: | The three-dimensional (3D) mechanical response of the cornea to intraocular pressure (IOP) elevation has not been previously reported. In this study, we use an ultrasound speckle tracking technique to measure the 3D displacements and strains within the central 5.5mm of porcine corneas during the whole globe inflation. Inflation tests were performed on dextran-treated corneas (treated with a 10% dextran solution) and untreated corneas. The dextran-treated corneas showed an inflation response expected of a thin spherical shell, with through-thickness thinning and in-plane stretch, although the strain magnitudes exhibited a heterogeneous spatial distribution from the central to more peripheral cornea. The untreated eyes demonstrated a response consistent with swelling during experimentation, with through-thickness expansion overriding the inflation response. The average volume ratios obtained in both groups was near 1 confirming general incompressibility, but local regions of volume loss or expansion were observed. These results suggest that biomechanical measurements in 3D provide important new insight to understand the mechanical response of ocular tissues such as the cornea. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|