Development of group B meningococcal vaccine: a progress review

Autor: Wei ZHAO, Shuang BAI, Yan-li KANG
Jazyk: čínština
Rok vydání: 2022
Předmět:
Zdroj: Zhongguo gonggong weisheng, Vol 38, Iss 8, Pp 1088-1092 (2022)
Druh dokumentu: article
ISSN: 1001-0580
DOI: 10.11847/zgggws1137414
Popis: Epidemic cerebrospinal meningitis is a respiratory infectious disease caused by Neisseria meningitidis, most commonly manifesting as meningitis and septicaemia. Due to the lack of effective prevention measures, serogroup B Neisseria meningitidis (MenB) has become one of dominant epidemic bacterial groups. In recent years, the emergence of reverse vaccinology has greatly promoted the research on serogroup B meningococcal vaccine, and researches on the vaccine have also made a breakthrough. In order to develop a more effective meningococcal vaccine, this article reviews the research progress on new protein antigen vaccine, outer membrane vesicle vaccine and recombinant protein vaccine in the field of MenB vaccine.
Databáze: Directory of Open Access Journals