Egg white hydrolysate prevents reproductive impairments induced by cadmium in rats

Autor: José Eudes Gomes Pinheiro, Júnior, Caroline Silveira Martinez, Paola Zambelli Moraes, José Eduardo Stasiaki, Maria Elisa Trost, Dalton Valentim Vassallo, Fernando Barbosa, Junior, Franck Maciel Peçanha, Francielli Weber Santos Cibin, Marta Miguel, Giulia Alessandra Wiggers
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Functional Foods, Vol 67, Iss , Pp 103823- (2020)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2020.103823
Popis: Here, we investigated the ability of an egg white hydrolysate (EWH) to counteract the reproductive toxic effects induced by Cd in rats. 3-month-old male Wistar rats were treated for 14 days: (a) Untreated group (distilled water i.p.); (b) Cd group (CdCl2 at 1 mg/kg body weight i.p.); (c) EWH group (1 g/kg body weight/day per gavage); (d) CdEWH group (CdCl2 with EWH). Cd exposure was able to be accumulated in testis and epididymis, increasing oxidative stress and compromising sperm quality and daily sperm production. Co-treatment with EWH prevented increased deposition of Cd in testis (Untreated: 0.04 ± 0.02; Cd: 4.68 ± 1.03*; EWH: 0.01 ± 0.00; CdEWH: 1.85 ± 0.25# μg Cd/g dry tissue p
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