Assessment of the relevance of osmolality measurement as a criterion for the stability of solutions
| Autor: | Vigneron Jean, Sacrez Matthieu, D’Huart Élise, Demoré Béatrice |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Pharmaceutical Technology in Hospital Pharmacy, Vol 8, Iss 1, Pp 20235-8 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2365-2411 2365-242X |
| DOI: | 10.1515/pthp-2022-0008 |
| Popis: | The measurement of osmolality is used by many authors as an additional stability criterion of a drug in solution. In the current state of knowledge, no scientific publication correlates the osmolality values and the stability of a solution. To study the relevance of this analytical technique by measuring the osmolality of injectable solutions whose instability has been chemically demonstrated by high performance liquid chromatography (HPLC). |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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