Autor: |
Seraina von Moos, Gesa Schalk, Thomas F. Mueller, Guido Laube |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
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Zdroj: |
Immunity & Ageing, Vol 16, Iss 1, Pp 1-8 (2019) |
Druh dokumentu: |
article |
ISSN: |
1742-4933 |
DOI: |
10.1186/s12979-019-0149-8 |
Popis: |
Abstract Background Older age at organ transplantation is associated with increased risk of infection and malignancy but reduced risk of cellular rejection. De novo donor-specific anti-HLA antibodies (dnDSA), are key biomarkers associated with reduced long-term allograft survival, yet there is a lack of data focusing on age-associated changes. Methods Development of dnDSA was restrospectively analyzed in all subjects who received a kidney transplant at the University Hospital Zurich between 01/2006 and 02/2015. Follow up continued until 03/2016. The incidence of dnDSA in different age categories was compared with special focus on the extremes of age: children |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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