Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men

Autor: Ryutaro Matsumoto, Katsuhiko Tsunekawa, Yoshifumi Shoho, Yoshimaro Yanagawa, Nobuo Kotajima, Shingo Matsumoto, Osamu Araki, Takao Kimura, Katsuyuki Nakajima, Masami Murakami
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-9 (2019)
Druh dokumentu: article
ISSN: 1476-511X
DOI: 10.1186/s12944-019-1014-7
Popis: Abstract Background Two important regulators for circulating lipid metabolisms are lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL). In relation to this, glycosylphosphatidylinositol anchored high-density lipoprotein binding protein 1 (GPIHBP1) has been shown to have a vital role in LPL lipolytic processing. However, the relationships between skeletal muscle mass and lipid metabolism, including LPL, GPIHBP1, and HTGL, remain to be elucidated. Demonstration of these relationships may lead to clarification of the metabolic dysfunctions caused by sarcopenia. In this study, these relationships were investigated in young Japanese men who had no age-related factors; participants included wrestling athletes with abundant skeletal muscle. Methods A total of 111 young Japanese men who were not taking medications were enrolled; 70 wrestling athletes and 41 control students were included. The participants’ body compositions, serum concentrations of lipoprotein, LPL, GPIHBP1 and HTGL and thyroid function test results were determined under conditions of no extreme dietary restrictions and exercises. Results Compared with the control participants, wrestling athletes had significantly higher skeletal muscle index (SMI) (p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje