Thyroid function, renal function, and depression: an association study

Autor: Hai Liang, Jin-min Wang, Xiao-qian Wei, Xiao-qin Su, Bi-xia Zhang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Psychiatry, Vol 14 (2023)
Druh dokumentu: article
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2023.1182657
Popis: ObjectiveTo investigate the correlations between thyroid function, renal function, and depression.MethodsClinical data of 67 patients with Major depressive disorder (MDD) and 36 healthy control subjects between 2018 and 2021 were collected to compare thyroid and renal function. Thyroid and renal functions of depressed patients were then correlated with the Hamilton Depression Rating Scale (HAMD) and the Hamilton Anxiety Rating Scale (HAMA).Spearman correlation analysis was used to find the correlation between renal function, thyroid function, and depression. A logistic regression was performed to find significant predictors of depression.ResultsTriiodothyronine protamine (T3), thyroxine (T4), free triiodothyronine protamine (FT3), uric acid, sodium, and anion gap were lower in the MDD group than in the control group (p
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