Cost of arthropathic diseases therapy with biologicals disease modifying drugs (bDMARs): a 5-year cost analysis at national level

Autor: Konstantin Tachkov, Vladimira Boyadzhieva, Ivan Manev, Nikolay Stoilov, Zornitsa Mitkova, Konstantin Mitov, Guenka Petrova
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Biotechnology & Biotechnological Equipment, Vol 36, Iss 1, Pp 828-837 (2022)
Druh dokumentu: article
ISSN: 13102818
1314-3530
1310-2818
DOI: 10.1080/13102818.2022.2131468
Popis: AbstractThis study analysed the changes in the reimbursed cost, prices and utilization of biological medicines for a 5-year time horizon, encompassing three major arthropathic diagnoses, rheumatoid arthritis (RA), psoriatic arthropathies (PsA) and ankylosing spondylitis (AS), from the point of view of the third-party payer in Bulgaria. National; population based; macroeconomic; top-down budget analysis was performed based on official data about the number of inhabitants, reimbursed diagnoses and medicines, reimbursed cost, treated patients, and prices of medicines. The utilization of medicines was calculated in DDD per 1000/inh/day. There was an increase of 41% in the number of patients treated with biological medicines. The reimbursement cost of biologicals increased by 21%; however, the per-patient reimbursement costs per diagnosis fell by 40% due to price decreases. Out of 21 reimbursed diagnoses, we saw a significant difference in prevalence (612 SD in 2016 to 1216 SD in 2020; p
Databáze: Directory of Open Access Journals
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