Estudo químico e atividades antiproliferativa, tripanocida e leishmanicida de Maxillaria picta
| Autor: | Thiago L. de Almeida, Josiane A. Monteiro, Greice K. P. Lopes, Lucas U. R. Chiavelli, Silvana M. de O. Santin, Cleuza C. da Silva, Vanessa Kaplum, Débora B. Scariot, Celso V. Nakamura, Ana L. T. G. Ruiz, João E. Carvalho, Ricardo T. de Faria, Armando M. Pomini |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Química Nova, Vol 37, Iss 7, Pp 1151-1157 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1678-7064 0100-4042 |
| DOI: | 10.5935/0100-4042.20140179 |
| Popis: | The chemical study of the orchid Maxillaria picta resulted in the isolation of the bioactive stilbenes phoyunbene B and phoyunbene C, in addition to four phenolic acids, one xanthone, steroidal compounds and two triterpenes. Crude extract, fractions, subfractions and the isolated xanthone were evaluated for anticancer activity against human tumor cell lines and against evolutionary forms of T. cruzi and L. amazonensis. The structures of the compounds were determined by GC-MS, and ¹H NMR, 13C NMR spectral methods as well as bidimensional techniques. |
| Databáze: | Directory of Open Access Journals |
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