Autor: |
Krzysztof P. Bzymek, James W. Puckett, Cindy Zer, Jun Xie, Yuelong Ma, Jeremy D. King, Leah H. Goodstein, Kendra N. Avery, David Colcher, Gagandeep Singh, David A. Horne, John C. Williams |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-018-03976-5 |
Popis: |
Meditope-Fab is a peptide-antibody complex potentially useful for drug delivery and diagnostic, but a short half-life prevents its use in vivo. Here the authors engineer the complex to improve its stability, create functionalized antibodies by click chemistry and use them for in vivo tumor imaging. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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