Efficacy of Mobile-Based Cognitive Behavioral Therapy on Lowering Low-density Lipoprotein Cholesterol Levels in Patients With Atherosclerotic Cardiovascular Disease: Multicenter, Prospective Randomized Controlled Trial

Autor: DuanBin Li, Tian Xu, DaQi Xie, MiaoYun Wang, ShuPing Sun, Min Wang, SiSi Zhang, XinRui Yang, ZhongNan Zhang, Shen Wang, Ming Kuang, Jia Tang, HongYing Liu, XuLin Hong, GuoSheng Fu, WenBin Zhang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Medical Internet Research, Vol 25, p e44939 (2023)
Druh dokumentu: article
ISSN: 1438-8871
DOI: 10.2196/44939
Popis: BackgroundElevated low-density lipoprotein cholesterol (LDL-C) is an established risk factor for atherosclerotic cardiovascular disease (ASCVD). However, low adherence to medication and lifestyle management has limited the benefits of lowering lipid levels. Cognitive behavioral therapy (CBT) has been proposed as a promising solution. ObjectiveThis trial aimed to evaluate the efficacy of mobile-based CBT interventions in lowering LDL-C levels in patients with ASCVD. MethodsThis multicenter, prospective, randomized controlled trial enrolled 300 patients with ASCVD, who were randomly assigned to the mobile-based CBT intervention group and the control group in a ratio of 1:1. The intervention group received CBT for ASCVD lifestyle interventions delivered by WeChat MiniApp: “CBT ASCVD.” The control group only received routine health education during each follow-up. The linear regression and logistic regression analyses were used to determine the effects of a mobile-based CBT intervention on LDL-C, triglyceride, C-reactive protein, the score of General Self-Efficacy Scale (GSE), quality of life index (QL-index), and LDL-C up-to-standard rate (
Databáze: Directory of Open Access Journals
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