Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers.

Autor: Amit Kumar, Elena E Giorgi, Joshua J Tu, David R Martinez, Joshua Eudailey, Michael Mengual, Manukumar Honnayakanahalli Marichannegowda, Russell Van Dyke, Feng Gao, Sallie R Permar
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: PLoS Pathogens, Vol 17, Iss 4, p e1009478 (2021)
Druh dokumentu: article
ISSN: 1553-7366
1553-7374
DOI: 10.1371/journal.ppat.1009478
Popis: Despite considerable reduction of mother-to-child transmission (MTCT) of HIV through use of maternal and infant antiretroviral therapy (ART), over 150,000 infants continue to become infected with HIV annually, falling far short of the World Health Organization goal of reaching
Databáze: Directory of Open Access Journals