The Hemostasis System During MARS Therapy and Plasma Sorption in Patients with Liver Cell Failure
| Autor: | L. F. Yeremeyeva, A. F. Yampolsky, I. B. Zabolotskikh, V. V. Menshchikov |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Общая реаниматология, Vol 6, Iss 5 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1813-9779 2411-7110 |
| DOI: | 10.15360/1813-9779-2010-5-35 |
| Popis: | Objective: to comparatively estimate major hemostatic parameters during plasma sorption (PS) and molecular adsorption recirculating system (MARS) therapy in patients with liver cell failure. Subjects and methods: Forty-one patients with liver cell failure were examined. The patients’ condition was rated using the APACHE III, SOFA, MODS, and Child-Pugh scales. As a complex of intensive therapy, all the patients were treated with extracorporeal techniques: MARS therapy in Group 1 (n=17) and plasma sorption in Group 2 (n=24). The patients’ age was 18 to 65 years. Results. MARS therapy, unlike PS, normalizes the parameters of coagulation hemostasis and stabilizes platelet counts within 5 days in the postperfusion period. MARS therapy is the procedure of choice for the treatment of patients with liver cell failure. Mortality was 35.3 and 54.2% in Groups 1 and 2, respectively. Key words: molecular adsorption recirculating system, plasma sorption, acute liver cell failure. |
| Databáze: | Directory of Open Access Journals |
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