| Autor: |
Katherine Laiton-Donato, Jose A. Usme-Ciro, Carlos Franco-Muñoz, Diego A. Álvarez-Díaz, Hector Alejandro Ruiz-Moreno, Jhonnatan Reales-González, Diego Andrés Prada, Sheryll Corchuelo, Maria T. Herrera-Sepúlveda, Julian Naizaque, Gerardo Santamaría, Magdalena Wiesner, Diana Marcela Walteros, Martha Lucia Ospina Martínez, Marcela Mercado-Reyes |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Frontiers in Medicine, Vol 8 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2296-858X |
| DOI: |
10.3389/fmed.2021.697605 |
| Popis: |
COVID-19 pandemics has led to genetic diversification of SARS-CoV-2 and the appearance of variants with potential impact in transmissibility and viral escape from acquired immunity. We report a new and highly divergent lineage containing 21 distinctive mutations (10 non-synonymous, eight synonymous, and three substitutions in non-coding regions). The amino acid changes L249S and E484K located at the CTD and RBD of the Spike protein could be of special interest due to their potential biological role in the virus-host relationship. Further studies are required for monitoring the epidemiologic impact of this new lineage. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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