OSOBENNOSTI METABOLIZMA KOSTNOY TKANI U BOL'NYKh ANKILOZIRUYuShchIM SPONDILOARTRITOM
| Autor: | S A Yushina, O V Bugrova, N A Ovchinnikova, I A Aleksandrova |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Остеопороз и остеопатии, Vol 14, Iss 2, Pp 15-18 (2011) |
| Druh dokumentu: | article |
| ISSN: | 2072-2680 2311-0716 |
| DOI: | 10.14341/osteo2011215-18 |
| Popis: | Objective: To define the specific features of bone metabolism and to estimate bone mineral density (BMD) in patients with ankylosing spondylitis (AS) Subjects and methods: Seventy-two patients (66 males and 6 females) with SA were examined. Markers of bone metabolism markers were assessed, by measuring the serum levels of osteocalcin (OC) and C-terminal telopeptides (bCrosslaps) by enzyme-linked immunoassay. Bone mineral density (BMD) was studied by distal forearm by dual-energy X-ray absorptiometry (DEXA) on a DexaScan DX-10 apparatus. BMD was estimated in women and men older 50 years by the T-test and in men under 50 years by the Z-test. Results: Low BMD was found by DEXA in 55% patients with SA., 7% patients had a vertebral fracture. The level of bCrosslaps was 0.52±0.37 ng/ml (p>0.05) and that of osteocalcin was 12,9±7,1 ng/ml (p |
| Databáze: | Directory of Open Access Journals |
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