| Autor: |
Joaquín Navarro del Hierro, Teresa Herrera, Tiziana Fornari, Guillermo Reglero, Diana Martin |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Journal of Functional Foods, Vol 40, Iss , Pp 484-497 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2017.11.032 |
| Popis: |
Saponins are bioactive compounds of increasing interest. The events that take place during digestion are highly related to their bioactivities, because saponins are poorly absorbed and have a long residence time in the intestinal tract. The poor bioavailability of saponins is explained by a sum of factors, but the more favorable properties of sapogenins result in higher bioavailability and bioactivity. The gastric and colonic transformations of saponins are relevant in the release of sapogenins. Saponins inhibit enzymes and cholesterol absorption, but specific chemical structures of saponins are relevant for an efficient activity. Finally, the recent research has pointed to saponins as “prebiotic-like” compounds. This review summarizes the current knowledge on the events that take place during digestion of saponins and sapogenins related to their bioactivities, with special emphasis on the factors that modulate their bioavailability, bioaccessibility, inhibition of digestive enzymes and cholesterol absorption, and the importance of the microbiota-saponins relationship. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect