| Autor: |
Toshiyuki Matsuura, Hiroki Kaneko, Kei Takayama, Rei Shibata, Keiko Kataoka, Seina Ito, Taichi Tsunekawa, Hideyuki Shimizu, Ayana Suzumura, Rina Namba, Yasuki Ito, Toyoaki Murohara, Hiroko Terasaki |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-7 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2415 |
| DOI: |
10.1186/s12886-020-01334-y |
| Popis: |
Abstract Background Previously, we showed that serum malondialdehyde (MDA) was significantly higher in patients with neovascular age-related macular degeneration (nAMD) than in those without AMD. The Diacron reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) tests are known markers of oxidative stress. The aim of this study was to use d-ROMs and BAP tests to evaluate changes in systemic oxidative stress in patients with nAMD. Methods Blood serum samples were collected from 34 patients with nAMD (mean age: 76.5 ± 7.7 years; 22 men) and 20 control subjects (mean age: 62.9 ± 14.0 years; 10 men), and d-ROMs and BAP tests were examined. Results In men, the mean level of d-ROMs for the nAMD patients was significantly higher than that for the controls (312.0 ± 52.4 vs. 275.1 ± 45.5 U.CARR, respectively; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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