Biochemical and histological changes in the heart of post-partum rats exposed to Natron

Autor: Yusuf Saidu, Maimuna Jumai Usman, Suleiman Ahmed Isa, Simeon Alabi Isezuo, Lawal Suleiman Bilbis, Saddiku Malam Sahabi, Ahmad Bello, Suleiman Alhaji Muhammad
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Indian Heart Journal, Vol 70, Iss 6, Pp 887-893 (2018)
Druh dokumentu: article
ISSN: 0019-4832
DOI: 10.1016/j.ihj.2017.12.002
Popis: Background: The customary puerperal practice of Natron consumption has been identified as one of the predisposing factors in the etiology of peripartum cardiomyopathy (PPCM). This study was designed to investigate the effect of Natron in postpartum Wistar albino rats. Methods: A total of 30 postpartum Wistar rats were exposed to different doses (50 mg/kg, 100 mg/kg, 200 mg/kg and 300 mg/kg) of Natron for 28 days. After the treatment, we carried out biochemical analyses and histological evaluations of kidney, liver and heart. Results: The study revealed that the exposure of postpartum rats to 100 mg/kg of Natron and above significantly (p
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