Limosilactobacillus reuteri L26 BiocenolTM and its exopolysaccharide: Their influence on rotavirus-induced immune molecules in enterocyte-like cells

Autor:	P Schusterova, D Mudronová, K Loziakova Penazziova, V Hajducková, T Csank
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	innate antivirus immunity lactic acid bacteria rva osu 6 type iii interferon Veterinary medicine SF600-1100
Zdroj:	Veterinární Medicína, Vol 69, Iss 5, Pp 169-176 (2024)
Druh dokumentu:	article
ISSN:	0375-8427 1805-9392
DOI:	10.17221/106/2023-VETMED
Popis:	This study aimed to evaluate the immunomodulatory effect of the probiotic Limosilactobacillus reuteri L26 BiocenolTM (L26) and its purified exopolysaccharide (EPS) with respect to antiviral innate immune response. In our experiment, we used porcine epithelial IPEC-J2 cells as a model of the intestinal barrier in a homologous infection by porcine Rotavirus A strain OSU6 (RVA). The production of selected molecules of non-specific humoral immunity was evaluated at the mRNA level. The EPS alone significantly increased the level of interferon λ3 (IFN-λ3) mRNA in the non-infected IPEC-J2 cells (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/91158e265505461cb57f9012b83518d8 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF