A Handheld Metabolic Device (Lumen) to Measure Fuel Utilization in Healthy Young Adults: Device Validation Study

Autor: Lorenz, Kent Arnold, Yeshurun, Shlomo, Aziz, Richard, Ortiz-Delatorre, Julissa, Bagley, James Robert, Mor, Merav, Kern, Marialice
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Interactive Journal of Medical Research, Vol 10, Iss 2, p e25371 (2021)
Druh dokumentu: article
ISSN: 1929-073X
DOI: 10.2196/25371
Popis: BackgroundMetabolic carts measure the carbon dioxide (CO2) produced and oxygen consumed by an individual when breathing to assess metabolic fuel usage (carbohydrates versus fats). However, these systems are expensive, time-consuming, and only available in health care laboratory settings. A small handheld device capable of determining metabolic fuel usage via CO2 from exhaled air has been developed. ObjectiveThe aim of this study is to evaluate the validity of a novel handheld device (Lumen) for measuring metabolic fuel utilization in healthy young adults. MethodsMetabolic fuel usage was assessed in healthy participants (n=33; mean age 23.1 years, SD 3.9 years) via respiratory exchange ratio (RER) values obtained from a metabolic cart as well as % CO2 from the Lumen device. Measurements were performed at rest in two conditions: fasting, and after consuming 150 grams of glucose, in order to determine changes in metabolic fuel usage. Reduced major axis regression and simple linear regression were performed to test for agreement between RER and Lumen % CO2. ResultsBoth RER and Lumen % CO2 significantly increased after glucose intake (P
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