Glucose metabolism reprogramming promotes immune escape of hepatocellular carcinoma cells

Autor: Qiuyue Zhang, Jinchen Liu, Haifeng Lin, Bo Lin, Mingyue Zhu, Mengsen Li
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 3, Pp 519-536 (2023)
Druh dokumentu: article
ISSN: 2692-3114
DOI: 10.37349/etat.2023.00149
Popis: Hepatocellular carcinoma (HCC) is a complex process that plays an important role in its progression. Abnormal glucose metabolism in HCC cells can meet the nutrients required for the occurrence and development of liver cancer, better adapt to changes in the surrounding microenvironment, and escape the attack of the immune system on the tumor. There is a close relationship between reprogramming of glucose metabolism and immune escape. This article reviews the current status and progress of glucose metabolism reprogramming in promoting immune escape in liver cancer, aiming to provide new strategies for clinical immunotherapy of liver cancer.
Databáze: Directory of Open Access Journals