X-Ray powder diffraction. The practical application of the method in the pharmaceutical expertise

Autor:	V. S. Kuzmin, V. V. Chernyshev, V. A. Yashkir, V. A. Merkulov
Jazyk:	ruština
Rok vydání:	2018
Předmět:	x-ray powder diffraction x-ray analysis substances of medicines index «identity» рентгеновская порошковая дифрактометрия рентгенофазовый анализ субстанции лекарственных средств показатель «подлинность» Medicine (General) R5-920
Zdroj:	Регуляторные исследования и экспертиза лекарственных средств, Vol 0, Iss 2, Pp 13-16 (2018)
Druh dokumentu:	article
ISSN:	3034-3062 3034-3453
Popis:	Method of X-ray phase analysis based on obtaining and analyzing the diffraction pattern resulting from the diffraction of x-rays scattered by electrons of the atoms of the irradiated polycrystalline sample. Using this method in the framework of a pre-registration examination the study of pharmaceutical substances temosolomide, form I of valacyclovir hydrochloride monohydrate and quetiapine fumarate (form I) to confirm their authenticity. The results obtained allowed to conclude that the claimant substance temosolomide is not primary, and the substance of valacyclovir does not meet the stated requirements in terms of "Authenticity".
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e90cab8eb1c444e889b4e70567726db3 Zobrazit plný text záznamu View record in DOAJ