Successful Treatment with High-Dose Chemotherapy Followed by Autologous Stem-Cell Transplantation in a Patient with Metastatic Germ Cell Tumor

Autor:	Jung Min Lee, Byung Woog Kang, Man-Hoon Han, Dong Won Baek
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	high-dose chemotherapy autologous hematopoietic cell transplantation germ cell tumor Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Case Reports in Oncology, Vol 14, Iss 2, Pp 998-1003 (2021)
Druh dokumentu:	article
ISSN:	1662-6575 00051675
DOI:	10.1159/000516755
Popis:	Although testicular germ cell tumors (GCTs) are known to curable disease even in cases with metastatic disease, patients in intermediate or poor-risk group may experience disease progression or refractory to the initial chemotherapy and needed second-line therapy. Long-term disease-free survival was unsatisfactory in relapsed/refractory patients with poor-risk factors and clinical trials for those patients are still insufficient. High-dose chemotherapy (HDCT) with stem-cell rescue may be an effective alternative for conventional chemotherapy-resistant patients who are eligible for transplantation. Herein, we present successful treatment experience with HDCT followed by autologous stem-cell transplantation in a severely ill patient with heavily pretreated metastatic GCT.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/90c8d3b26509489ab2f38052934e150e Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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