Cycloferon Efficacy of Therapy of Chronic Hepatitis B (Results of Randomized Multicentre Study)

Autor: T. V. Sologub, A. A. Shuldyakov, L. G. Goryacheva, I. P. Baranova, YU. N. Linkova, A. L. Kovalenko, M. G. Romantsov
Jazyk: ruština
Rok vydání: 2020
Předmět:
Zdroj: Антибиотики и Химиотерапия, Vol 55, Iss 9-10, Pp 37-41 (2020)
Druh dokumentu: article
ISSN: 0235-2990
Popis: The best therapeutic effect in the treatment of patients with chronic hepatitis B was observed with the use of cycloferon in the scheme of the antiviral therapy. The combination of cycloferon with lamivudine provided complete stable remission in 54.1% of the patients, whereas the use of а-interferon in combination with cycloferon provided remission in 44.1% of the lamivudine-resistant patients. The use of cycloferon in the therapy of chronic hepatitis B made it possible to lower the frequency and manifestation level of the side effects and prevented the lamivudine resistance development and generation of the virus mutants.
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