Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma

Autor: Christopher E. Lietz, Erik T. Newman, Andrew D. Kelly, David H. Xiang, Ziying Zhang, Caroline A. Luscko, Santiago A. Lozano-Calderon, David H. Ebb, Kevin A. Raskin, Gregory M. Cote, Edwin Choy, G. Petur Nielsen, Benjamin Haibe-Kains, Martin J. Aryee, Dimitrios Spentzos
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-03117-1
Popis: Christopher Lietz et al. examined genome-wide methylation in patient cohorts of primary osteosarcoma. Their results suggest that genomic hypomethylation is predictive of response to standard chemotherapy, and provide further insight into clinical implications of methylation patterns.
Databáze: Directory of Open Access Journals
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