Prognostic value of laboratory markers in patients with acute pulmonary embolism

Autor: Amany Omar Mohamed Omar, Yousef Ahmed Yousef Ahmed, Abd-Elazim Ahmed Abo Elfadl, Abeer Houssein Ali, Amal Abdallah Abdelrahman, Khaled Mohamed Khaled Ali
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Egyptian Journal of Bronchology, Vol 18, Iss 1, Pp 1-8 (2024)
Druh dokumentu: article
ISSN: 2314-8551
DOI: 10.1186/s43168-024-00293-y
Popis: Abstract Background Acute pulmonary embolism (APE) is a serious illness. Identifying prognostic factors for APE may help in the management of those patients. This study’s objective was to evaluate the prognostic value of laboratory markers in predicting right ventricular dysfunction (RVD) and 30-day mortality in pulmonary embolism patients. Methods Eighty patients with APE were enrolled and followed up for 30 days. Detailed echocardiography was done to evaluate RVD. All patients were subjected to arterial blood gas analysis, complete blood count (CBC), plasma concentration of C-reactive protein (CRP), serum D-dimer level, and serum troponin I level, and the following ratio were calculated: neutrophil-to-lymphocytic ratio (NLR), platelet to lymphocytic ratio (PLR), red cell distribution width (RDW), mean platelet volume (MPV), and alveolar to arterial gradient. Results Our results analysis revealed significantly elevated levels of median NLR, PLR, CRP, D-dimer, and troponin in both the RVD and non-survivor groups (P value
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