Predictors of Local Invasion in Infiltrative Basal Cell Carcinoma: Tumour Budding Outperforms the WHO Subtyping
| Autor: | Maria Teresa Fernandez-Figueras, Noelia Perez-Muñoz, Luis Puig, Rodolfo Posada-Caez, Rosa Ballester Victoria, Martha Henriquez, Eva Musulen |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Acta Dermato-Venereologica, Vol 104 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0001-5555 1651-2057 |
| DOI: | 10.2340/actadv.v104.40172 |
| Popis: | Tumour budding (TB) correlates with increased local invasion in various neoplasms. Certain basal cell carcinomas (BCCs) exhibit local aggressiveness. Detecting adverse prognostic factors in partial biopsies could aid in identifying cases with heightened local risk. The absolute number of TB (≤ 3 tumour cells) in excision specimens of 271 infiltrative BCCs (0: absent; 1: 1–2 foci; 2: ≥ 3 foci; 3: ≥ 10 foci), the histopathological subtype and depth of infiltration, perineural invasion, and other histological features were evaluated. A significant correlation was found between TB and both depth of infiltration (rho 0.445, p |
| Databáze: | Directory of Open Access Journals |
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