Efficacy of oral diclofenac as preemptive analgesic for pterygium surgery

Autor: Anabelle F. Galias, MD, Teofilo R. Bulosan, MD, Danilo Q. Reyno, MD, Amiel N. Rodriguez, MD, Rosalina T Babao
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Philippine Journal of Ophthalmology, Vol 33, Iss 1, Pp 13-16 (2008)
Druh dokumentu: article
ISSN: 0031-7659
Popis: Objective: To determine the efficacy of oral diclofenac as preemptive analgesic for pterygium excision. Methods: A prospective, randomized, controlled, double-blind clinical trial was carried out involving 30 patients diagnosed with pterygium. They were randomly assigned to receive either placebo or oral diclofenac. A single surgeon performed the same technique of pterygium excision. Pain scores were determined using visual-analog-scale (VAS) questionnaires handed out to participants 30 minutes and 24 hours after surgery. Collected data were analyzed using two-tailed t-test, chi-square, and Fisher’s exact test. Results: There was no statistical difference between VAS pain scores in both groups in the intra- (p = 0.33) and postoperative periods (p = 0.46). No statistically significant difference was noted on the intake (p = 0.68) and dose (0.18) of supplemental analgesia. There appeared to be a trend for lower pain scores in the intraoperative (VAS = 2.00 ± 1.89 for diclofenac vs. 2.73 ± 2.22 for control) and postoperative (VAS = 3.86 ± 2.92 for diclofenac vs. 4.60 ± 2.44 for control) periods with intake of diclofenac. This group also took less supplemental analgesics. Conclusion: The preemptive use of oral diclofenac showed a trend toward less intra-and postoperative pain, and less need for supplemental analgesics after pterygium surgery.
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