| Autor: |
Shun Zhang, Jing-Ze Li, Tao Du, Hai-Qiang Li, Ren-Hao Hu, Chi-Ye Ma, Xi-Mao Cui, Chun Song, Xiao-Hua Jiang |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Canadian Journal of Gastroenterology and Hepatology, Vol 2022 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2291-2797 |
| DOI: |
10.1155/2022/3953004 |
| Popis: |
Background. Traditionally, serum CEA and CA19-9 levels are good prognostic factors for gastric cancer. Many gastric cancer patients do not have elevated CEA or CA19-9 levels even at a very advanced stage. This study investigates the significance of the modified Glasgow prognostic score (mGPS) for the survival of gastric cancer patients with normal CEA and CA19-9. Methods. We retrospectively examined 488 curatively resected gastric cancer patients with normal preoperative serum levels of CEA and CA19-9 to evaluate the prognostic ability of mGPS for overall survival. The prognostic significance was analyzed by univariate and multivariate analyses. Results. Age, hemoglobin, white cell count, and neutrophils were each significantly correlated with the mGPS. Multivariate analyses showed that tumor location (HR, 0.803; 95% CI, 0.667–0.966; P=0.020), TNM stage (HR, 2.714; 95% CI, 2.250–3.275; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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