| Autor: |
Andrea Sucasas Alonso, Alejandro Avila-Alvarez, Marina Combarro Eiriz, Cristina Martínez Roca, Pedro Yáñez Gómez, Alejandra Codias López, Jose Luis Fernández Trisac, Sonia Pértega Díaz |
| Jazyk: |
Spanish; Castilian |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Anales de Pediatría (English Edition), Vol 91, Iss 4, Pp 237-243 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2341-2879 |
| DOI: |
10.1016/j.anpede.2018.12.005 |
| Popis: |
Objective: To evaluate the prevalence of non-approved prescriptions (off-label and unlicensed) in a neonatal intensive care unit (NICU), and to describe factors of the neonate associated with its use. Materials and methods: Observational prospective study in a level III NICU during a 6-month period. Every prescription was analysed using the summary of product characteristics as a reference. A sequential algorithm was used to create a classification of prescriptions based on current status: approved, unlicensed, off-label (by age, route of administration, dosage, or indication). Results: The study included 84 patients and 564 prescriptions. A total of 127 (22.5%) prescriptions were considered off-label, and 45 (8%) were considered unlicensed. More than half (59.5%) of the patients received at least one of these drugs, and this increases to 100% among very preterm neonates and surgical patients (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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