ELECTRON MICROSCOPIC PROPERTIES OF A NEW ANTIMICROBIAL NANODRUG BASED ON COPPER-CALCIUM HYDROXIDE COMPOUND
| Autor: | V.A. RUMYANTSEV, G.A. FROLOV, A.V. BLINOVA, YA .N. KARASENKOV, E.V. BITYUKOVA |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Паёми Сино, Vol 23, Iss 4, Pp 532-541 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2074-0581 2959-6327 |
| DOI: | 10.25005/2074-0581-2021-23-4-532-541 |
| Popis: | Objective: To study the structural arrangement of the copper-calcium hydroxide (CCH), a commercially available dental paste used in aqueous suspension, as well as a new antimicrobial nanodrug based on CCH and a hydrosol of copper nanoparticles and copper (II) oxide. Methods: Dental paste Cupral® manufactured by "Humanchemie GmbH" (Germany) was investigated. Immediately prior to the study, it was diluted with either distilled water or a hydrosol of copper nanoparticles and copper (II) oxide in a ratio of 1:2. The hydrosol was obtained in the Department of Physical Chemistry laboratory at the National University of Science and Technology "MISiS", using the method of condensation of low-temperature plasma in a spark discharge. The microstructure of the obtained samples was analyzed using a transmission electron microscope (TEM), LEO 912 AB OMEGA (Carl Zeiss, Oberkochen, Germany). Results: Dilution of CCH with a hydrosol of copper nanoparticles and copper (II) oxide results in forming a complex nanosized composite structure. Nanoparticles in the dispersed phase penetrate the surface layers of CCH particles, which are crystalline hydrates of copper (II) oxide and calcium oxide. Conclusion: The discovered phenomenon could be helpful in the design of a new technology of nanoimpregnation of the tooth root dentin in endodontic and periodontal treatment, which does not require additional electrophoresis. |
| Databáze: | Directory of Open Access Journals |
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