Interpretation of androgen and anti-Mullerian hormone profiles in a Hispanic cohort of 5- to 8-year-old girls with premature adrenarche
| Autor: | Preneet Cheema Brar, Elena Dingle, Daniela Ovadia, Sarah Pivo, Veeramac Prasad, Raphael David |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Annals of Pediatric Endocrinology & Metabolism, Vol 23, Iss 4, Pp 210-214 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2287-1012 2287-1292 |
| DOI: | 10.6065/apem.2018.23.4.210 |
| Popis: | Purpose Premature adrenarche (PA) often leads to polycystic ovary syndrome (PCOS). Higher anti-mullerian hormone (AMH) levels are reported in PCOS. We studied the androgen profile and AMH profiles in Hispanic girls with PA (aged 5–8 years) and age and body mass index (BMI) matched controls. Methods Retrospective review of electronic medical records of girls who met the inclusion criteria for premature adrenarche were done. Results PA girls (n=76) were matched to control girls (n=12) for age (mean±standard deviation) (6.7±1 years vs. 6.2±1.3 years) and BMI (20±10 kg/m2 vs. 17.8±2.7 kg/m2). Dehydroepiandrostenedione sulfate (63.3±51.3 μg/dL vs. 29.8±17.3 μg/dL, P |
| Databáze: | Directory of Open Access Journals |
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